<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-00812184</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-17T22:58:40+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Spatial Information and Boolean Genetic Regulatory Networks.</title>
            <author role="crp">
              <persName>
                <forename type="first">Matthieu</forename>
                <surname>Manceny</surname>
              </persName>
              <email type="md5">7893d8ab99a3cf37ae6e35b455085fcb</email>
              <email type="domain">ibisc.univ-evry.fr</email>
              <idno type="idhal" notation="numeric">855604</idno>
              <idno type="halauthorid" notation="string">364811-855604</idno>
              <idno type="IDREF">https://www.idref.fr/120741148</idno>
              <idno type="VIAF">https://viaf.org/viaf/207197339</idno>
              <idno type="ISNI">http://isni.org/isni/000000035830435X</idno>
              <affiliation ref="#struct-3207"/>
              <affiliation ref="#struct-104071"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marc</forename>
                <surname>Aiguier</surname>
              </persName>
              <email type="md5">d3e94459f59500b917356885e15c2625</email>
              <email type="domain">ibisc.univ-evry.fr</email>
              <idno type="idhal" notation="string">marc-aiguier</idno>
              <idno type="idhal" notation="numeric">1033739</idno>
              <idno type="halauthorid" notation="string">366486-1033739</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-0154-0909</idno>
              <idno type="IDREF">https://www.idref.fr/068446748</idno>
              <idno type="VIAF">https://viaf.org/viaf/162199892</idno>
              <idno type="ISNI">http://isni.org/isni/0000000111547667</idno>
              <affiliation ref="#struct-3207"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Pascale</forename>
                <surname>Le Gall</surname>
              </persName>
              <email type="md5">5513f4bca5ec36d322086c1037ab3a3a</email>
              <email type="domain">centralesupelec.fr</email>
              <idno type="idhal" notation="string">pascale-le-gall</idno>
              <idno type="idhal" notation="numeric">170929</idno>
              <idno type="halauthorid" notation="string">40654-170929</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-8955-6835</idno>
              <idno type="IDREF">https://www.idref.fr/081059310</idno>
              <idno type="VIAF">https://viaf.org/viaf/208139891</idno>
              <affiliation ref="#struct-3207"/>
              <affiliation ref="#struct-104071"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Joan</forename>
                <surname>Hérisson</surname>
              </persName>
              <email type="md5">f01144d13e07c075a6a8fa7f5d724ab3</email>
              <email type="domain">univ-evry.fr</email>
              <idno type="idhal" notation="string">joan-herisson</idno>
              <idno type="idhal" notation="numeric">1327225</idno>
              <idno type="halauthorid" notation="string">205647-1327225</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-9741-0847</idno>
              <idno type="IDREF">https://www.idref.fr/084538821</idno>
              <idno type="VIAF">https://viaf.org/viaf/217255910</idno>
              <idno type="ISNI">http://isni.org/isni/0000000359566386</idno>
              <affiliation ref="#struct-104071"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Ivan</forename>
                <surname>Junier</surname>
              </persName>
              <email type="md5">2f5f1e281ddec2071adf1e9cca832abe</email>
              <email type="domain">univ-grenoble-alpes.fr</email>
              <idno type="idhal" notation="string">ijunier</idno>
              <idno type="idhal" notation="numeric">16039</idno>
              <idno type="halauthorid" notation="string">1065-16039</idno>
              <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=UiHvu5AAAAAJ&amp;hl=fr&amp;oi=ao</idno>
              <idno type="IDREF">https://www.idref.fr/059399627</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-3522-9599</idno>
              <affiliation ref="#struct-104071"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">François</forename>
                <surname>Képès</surname>
              </persName>
              <email type="md5">0fb1b7a4c749991ecc5b66fff2a52e53</email>
              <email type="domain">genopole.cnrs.fr</email>
              <idno type="idhal" notation="numeric">855679</idno>
              <idno type="halauthorid" notation="string">132004-855679</idno>
              <idno type="IDREF">https://www.idref.fr/060224371</idno>
              <idno type="VIAF">https://viaf.org/viaf/2654417</idno>
              <idno type="ISNI">http://isni.org/isni/0000000119184469</idno>
              <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=om8F_QMAAAAJ</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-5766-4957</idno>
              <affiliation ref="#struct-104071"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Marc</forename>
                <surname>Aiguier</surname>
              </persName>
              <email type="md5">e65ed4d05e927b50c8ddfa7eb4be4361</email>
              <email type="domain">centralesupelec.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2013-04-12 11:01:21</date>
              <date type="whenWritten">2009-04-01</date>
              <date type="whenModified">2026-03-22 16:40:59</date>
              <date type="whenReleased">2013-04-12 11:24:06</date>
              <date type="whenProduced">2008-04-08</date>
              <date type="whenEndEmbargoed">2013-04-12</date>
              <ref type="file" target="https://centralesupelec.hal.science/hal-00812184v1/document">
                <date notBefore="2013-04-12"/>
              </ref>
              <ref type="file" subtype="author" n="1" target="https://centralesupelec.hal.science/hal-00812184v1/file/grn.pdf" id="file-812184-147187">
                <date notBefore="2013-04-12"/>
              </ref>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="180107">
                <persName>
                  <forename>Marc</forename>
                  <surname>Aiguier</surname>
                </persName>
                <email type="md5">e65ed4d05e927b50c8ddfa7eb4be4361</email>
                <email type="domain">centralesupelec.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-00812184</idno>
            <idno type="halUri">https://centralesupelec.hal.science/hal-00812184</idno>
            <idno type="halBibtex">manceny:hal-00812184</idno>
            <idno type="halRefHtml">&lt;i&gt;Bioinformatics and Computational Biology (BICoB)&lt;/i&gt;, Apr 2008, New Orleans, United States. pp.270-281, &lt;a target="_blank" href="https://dx.doi.org/10.1007/978-3-642-00727-9_26"&gt;&amp;#x27E8;10.1007/978-3-642-00727-9_26&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Bioinformatics and Computational Biology (BICoB), Apr 2008, New Orleans, United States. pp.270-281, &amp;#x27E8;10.1007/978-3-642-00727-9_26&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://about.hal.science/hal-authorisation-v1/">HAL Authorization<ref corresp="#file-812184-147187"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="EC-PARIS">Ecole Centrale Paris</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-EVRY">Université d'Evry-Val d'Essonne</idno>
            <idno type="stamp" n="ECP-DR">ECP-DR</idno>
            <idno type="stamp" n="MAS">Laboratoire Mathématiques Appliquées aux Systèmes</idno>
            <idno type="stamp" n="MICS">Mathématiques et Informatique pour la Complexité et les Systèmes</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="invited" n="0">No</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
            <note type="proceedings" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Spatial Information and Boolean Genetic Regulatory Networks.</title>
                <author role="crp">
                  <persName>
                    <forename type="first">Matthieu</forename>
                    <surname>Manceny</surname>
                  </persName>
                  <email type="md5">7893d8ab99a3cf37ae6e35b455085fcb</email>
                  <email type="domain">ibisc.univ-evry.fr</email>
                  <idno type="idhal" notation="numeric">855604</idno>
                  <idno type="halauthorid" notation="string">364811-855604</idno>
                  <idno type="IDREF">https://www.idref.fr/120741148</idno>
                  <idno type="VIAF">https://viaf.org/viaf/207197339</idno>
                  <idno type="ISNI">http://isni.org/isni/000000035830435X</idno>
                  <affiliation ref="#struct-3207"/>
                  <affiliation ref="#struct-104071"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marc</forename>
                    <surname>Aiguier</surname>
                  </persName>
                  <email type="md5">d3e94459f59500b917356885e15c2625</email>
                  <email type="domain">ibisc.univ-evry.fr</email>
                  <idno type="idhal" notation="string">marc-aiguier</idno>
                  <idno type="idhal" notation="numeric">1033739</idno>
                  <idno type="halauthorid" notation="string">366486-1033739</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-0154-0909</idno>
                  <idno type="IDREF">https://www.idref.fr/068446748</idno>
                  <idno type="VIAF">https://viaf.org/viaf/162199892</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000111547667</idno>
                  <affiliation ref="#struct-3207"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Pascale</forename>
                    <surname>Le Gall</surname>
                  </persName>
                  <email type="md5">5513f4bca5ec36d322086c1037ab3a3a</email>
                  <email type="domain">centralesupelec.fr</email>
                  <idno type="idhal" notation="string">pascale-le-gall</idno>
                  <idno type="idhal" notation="numeric">170929</idno>
                  <idno type="halauthorid" notation="string">40654-170929</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-8955-6835</idno>
                  <idno type="IDREF">https://www.idref.fr/081059310</idno>
                  <idno type="VIAF">https://viaf.org/viaf/208139891</idno>
                  <affiliation ref="#struct-3207"/>
                  <affiliation ref="#struct-104071"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Joan</forename>
                    <surname>Hérisson</surname>
                  </persName>
                  <email type="md5">f01144d13e07c075a6a8fa7f5d724ab3</email>
                  <email type="domain">univ-evry.fr</email>
                  <idno type="idhal" notation="string">joan-herisson</idno>
                  <idno type="idhal" notation="numeric">1327225</idno>
                  <idno type="halauthorid" notation="string">205647-1327225</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-9741-0847</idno>
                  <idno type="IDREF">https://www.idref.fr/084538821</idno>
                  <idno type="VIAF">https://viaf.org/viaf/217255910</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000359566386</idno>
                  <affiliation ref="#struct-104071"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Ivan</forename>
                    <surname>Junier</surname>
                  </persName>
                  <email type="md5">2f5f1e281ddec2071adf1e9cca832abe</email>
                  <email type="domain">univ-grenoble-alpes.fr</email>
                  <idno type="idhal" notation="string">ijunier</idno>
                  <idno type="idhal" notation="numeric">16039</idno>
                  <idno type="halauthorid" notation="string">1065-16039</idno>
                  <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=UiHvu5AAAAAJ&amp;hl=fr&amp;oi=ao</idno>
                  <idno type="IDREF">https://www.idref.fr/059399627</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-3522-9599</idno>
                  <affiliation ref="#struct-104071"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">François</forename>
                    <surname>Képès</surname>
                  </persName>
                  <email type="md5">0fb1b7a4c749991ecc5b66fff2a52e53</email>
                  <email type="domain">genopole.cnrs.fr</email>
                  <idno type="idhal" notation="numeric">855679</idno>
                  <idno type="halauthorid" notation="string">132004-855679</idno>
                  <idno type="IDREF">https://www.idref.fr/060224371</idno>
                  <idno type="VIAF">https://viaf.org/viaf/2654417</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000119184469</idno>
                  <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=om8F_QMAAAAJ</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-5766-4957</idno>
                  <affiliation ref="#struct-104071"/>
                </author>
              </analytic>
              <monogr>
                <meeting>
                  <title>Bioinformatics and Computational Biology (BICoB)</title>
                  <date type="start">2008-04-08</date>
                  <date type="end">2009-04-10</date>
                  <settlement>New Orleans</settlement>
                  <country key="US">United States</country>
                </meeting>
                <editor>Sanguthevar Rajasekaran</editor>
                <imprint>
                  <publisher>Springer-Verlag</publisher>
                  <biblScope unit="serie">LNCS</biblScope>
                  <biblScope unit="volume">5462</biblScope>
                  <biblScope unit="pp">270-281</biblScope>
                  <date type="datePub">2009-04-01</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1007/978-3-642-00727-9_26</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Discrete Mathematical Modelling</term>
                <term xml:lang="en">Dynamics</term>
                <term xml:lang="en">Spatial Information</term>
                <term xml:lang="en">Gene Regulatory Networks</term>
              </keywords>
              <classCode scheme="halDomain" n="info.info-bi">Computer Science [cs]/Bioinformatics [q-bio.QM]</classCode>
              <classCode scheme="halDomain" n="sdv.bibs">Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]</classCode>
              <classCode scheme="halTypology" n="COMM">Conference papers</classCode>
              <classCode scheme="halOldTypology" n="COMM">Conference papers</classCode>
              <classCode scheme="halTreeTypology" n="COMM">Conference papers</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>In the course of understanding the functioning of cellular processes, modelling frameworks for biological networks are mandatory in order to reason on the models and their properties. One of the main problems with such modelling frameworks is to determine the dynamics of gene regulatory networks (GRN). Formal techniques, most of them based on model checking, have been applied to select valid dynamics, that is dynamics consistent with biological experiments expressed by temporal properties. The problem is that these formal techniques rapidly become intractable because dynamics associated to the GRN are most of the time very numerous. Recently, it has been observed in in vivo experiments and in genomic and transcriptomic studies, that spatial information are useful to better understand both the mechanisms and the dynamics of GRN. In this paper we propose to extend the modelling framework of R. Thomas in order to introduce such spatial information between genes, and we will show how these further informations allow us to restrict the number of dynamics to consider.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-3207" status="OLD">
          <orgName>Mathématiques Appliquées aux Systèmes - EA 4037</orgName>
          <orgName type="acronym">MAS</orgName>
          <desc>
            <address>
              <addrLine>Grande Voie des Vignes 92295 Châtenay-Malabry</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.mas.ecp.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1806510" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-104071" status="VALID">
          <orgName>Programme d'Épigénomique</orgName>
          <desc>
            <address>
              <addrLine>Genopole 523, place des Terrasses 91034 EVRY CEDEX</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300306" type="direct"/>
            <relation name="UPS3201" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-1806510" status="OLD">
          <orgName>École centrale Paris</orgName>
          <date type="start">1829-01-01</date>
          <date type="end">2015-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300306" status="VALID">
          <idno type="IdRef">030820529</idno>
          <idno type="ISNI">0000000121805818</idno>
          <idno type="ROR">https://ror.org/00e96v939</idno>
          <idno type="Wikidata">Q1531014</idno>
          <orgName>Université d'Évry-Val-d'Essonne</orgName>
          <orgName type="acronym">UEVE</orgName>
          <date type="start">1991-07-22</date>
          <desc>
            <address>
              <addrLine>Boulevard François Mitterrand 91025 Evry Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-evry.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>