%0 Journal Article %T Modeling the continuous lactic acid production process from wheat flour %+ Laboratoire des signaux et systèmes (L2S) %+ Laboratoire de Génie des Procédés et Matériaux - EA 4038 (LGPM) %+ Moulins Soufflet %A Gonzalez, Karen Vanessa %A Tebbani, Sihem %A Lopes, Filipa %A Thorigné, Aurore %A Givry, Sebastien %A Dumur, Didier %A Pareau, Dominique %< avec comité de lecture %@ 0175-7598 %J Applied Microbiology and Biotechnology %I Springer Verlag %P pp 147–159 %8 2016-01 %D 2016 %R 10.1007/s00253-015-6949-7 %K Lactic acid production Continuous process modeling Wheat flour Production rate maximization %Z Engineering Sciences [physics]/Chemical and Process Engineering %Z Engineering Sciences [physics]/AutomaticJournal articles %X A kinetic model of the simultaneous saccharification, protein hydrolysis, and fermentation (SSPHF) process for lactic acid production from wheat flour has been developed. The model describes the bacterial growth, substrate consumption, lactic acid production, and maltose hydrolysis. The model was fitted and validated with data from SSPHF experiments obtained under different dilution rates. The results of the model are in good agreement with the experimental data. Steady state concentrations of biomass, lactic acid, glucose, and maltose as function of the dilution rate were predicted by the model. This steady state analysis is further useful to determine the operating conditions that maximize lactic acid productivity. %G English %L hal-01256880 %U https://centralesupelec.hal.science/hal-01256880 %~ CNRS %~ UNIV-PSUD %~ SUP_LSS %~ LGPM %~ SUP_SYSTEMES %~ CENTRALESUPELEC %~ TDS-MACS %~ UNIV-PARIS-SACLAY %~ UNIV-PSUD-SACLAY %~ CENTRALESUPELEC-SACLAY %~ CHAIRE-BIOTECH-CS %~ CS-MODEL %~ CS-BIOTRANSFO %~ GS-ENGINEERING %~ GS-COMPUTER-SCIENCE