This paper describes a methodology for the optimization of complex actuation systems, using analog simulations and an evolutionary algorithm. Our proposal consists of the development of an automated design framework that helps the designer to quickly complete a presiz-ing step while ensuring that multidomain requirements are met within short development times typical of automotive industry. Multiphysics constraints can be handled, allowing the sizing of a complete automotive mechatronic system. The effectiveness of the methodology is demonstrated in the case of an exhaust gas recirculation valve. Electrical, mechanical, thermal, and magnetic requirements are met while a minimal volume is reached.