The concept of Responsible Innovation holds that any innovation should take into account the balance of economic, ethical, social and sustainable aspects throughout the entire project in a manner that shows care for the future being constructed. However, as this concept is recent, originates in the context of the European Union and addresses issues of the Global North, critics have called for improvements in the way the concept is formulated. This article aims to establish a broader perspective to support the development of the concept of Responsible Innovation, which means discussing its main premises to highlight its critical aspects related to contextual terms, supporting a view to adapt it for use in different countries under various requirements and circumstances, thus facilitating its implementation on the path to innovation. Thus, an integrative review was developed. From an analysis of articles chosen based on research criteria, a useful theoretical framework was formed to fill the gaps in Responsible Innovation , comparing its perspectives to a traditional innovation, establishing a concept capable of yielding the expected benefits.