In this paper it is proposed to extend the result described in Khalil and Praly (2014) and the references therein, regarding the high-gain observer-based nonlinear control to the case of systems with diffusion sensor dynamic. Based on some usual hypotheses, we provide sufficient conditions involving the high-gain parameter and the length on the PDE sensor. In fact it is brought into light an explicit trade off between them: the larger the observer gain, the smaller the length of the PDE sensor needs to be. The stability analysis of the closed loop system is based on a Lyapunov functional.