Progressive multiple alignment based on pyramidal classification and applied to multi-domain proteins - CentraleSupélec Access content directly
Conference Papers Year : 2004

Progressive multiple alignment based on pyramidal classification and applied to multi-domain proteins

Abstract

In spite of the increasing efficiency of multiple alignment programs, ClustalW still remains the most used algorithm for its good compromise between computing needs and accuracy. We propose to develop a progressive algorithm of the Clustal type with the advantages of a mixed strategy, i.e. combining local and global alignments. For this purpose, we replace the Neighbor-Joining algorithm by a pyramidal classification in order to compute the guide structure. A simple example is given to illustrate this new method.
No file

Dates and versions

hal-00262062 , version 1 (10-03-2008)

Identifiers

  • HAL Id : hal-00262062 , version 1

Cite

Jean-Christophe Aude, Géraldine Polaillon, Laure Vescovo, Jean-Loup Risler. Progressive multiple alignment based on pyramidal classification and applied to multi-domain proteins. 12th International Conference on Intelligent System for Molecular Biology (ISMB) and 3rd European Conference on Computational Biology (ECCB), Jul 2004, Glasgow, United Kingdom. pp.187. ⟨hal-00262062⟩
17 View
0 Download

Share

Gmail Facebook X LinkedIn More