In wireless communication, interference between two radio systems may occur when they operate at close frequency bands, sharing the same environment at the same time. Such systems coexist if both of them perform correctly in the presence of the other. To ensure their coexistence, Elec- tromagnetic Compatibility (EMC) is used to specify rules within standardization bodies. According to current EMC standards, the radio spectrum has been divided into non-overlapping bands often with exclusive access. However, nowadays there is a prolif- eration of new digital systems sharing common frequency bands because the spectrum is a limited resource. Many of them are operating in unlicensed bands regulated by The International Telecommunications Union (ITU), for example the 2.45 GHz Industrial, Scientific and Medical (ISM) band. The frequency allocation is also changing with the emergence of digital systems and this is the case for white spaces in the broadcast television (TV) spectrum. To avoid high interference levels, it is necessary to consider some parameters related to signal variations, repre- senting more accurately the environment. Some techniques have been proposed in the literature to reduce interference levels but they are applied to specific sharing studies. Hence, we evaluate in this paper the impact of time-frequency considerations for radio coexistence. We show that EMC studies are more precise and more representative of the reality when additional parameters relevant to the time domain are taken into account in the analysis framework. We illustrate these concepts through a specific study case. We evaluate the results for different system parameters, first considering that both of them occupy the same band and then assuming that they use overlapping but non-equal frequency bands.