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Journal Articles Mathematics in Computer Science Year : 2011

Embedding of biological regulatory networks and property preservation

Abstract

In the course of understanding biological regulatory networks (BRN), scientists usually start by studying small BRNs that they believe to be of particular importance to represent a biological function, and then, embed them in a larger network. Such a reduction can lead to neglect relevant regulations and to study a network whose properties can be very different from the properties of this network viewed as a part of the whole. In this paper we study, from a logical point of view, on which conditions concerning both networks, properties can be inherited by BRNs from sub-BRNs.We give some conditions on the nature of the network embeddings ensuring that dynamic properties on the embedded sub-BRNs are preserved at the level of the whole BRN.
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Dates and versions

hal-00782867 , version 1 (11-04-2013)

Identifiers

  • HAL Id : hal-00782867 , version 1

Cite

Mbarka Mabrouki, Marc Aiguier, Jean-Paul Comet, Pascale Le Gall, Adrien Richard. Embedding of biological regulatory networks and property preservation. Mathematics in Computer Science, 2011, 5 (1), pp.263-288. ⟨hal-00782867⟩
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